Microembolism and Catheter Ablation II
| Autor: | Nicki M. Reinking, Jon F. Urban, Linnea Lentz, Nicole Kirchhof, Thomas Deneke, Noah Barka, David E. Haines, Mark G. Stewart, Emanuel Kanal, Franck Halimi |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Time Factors medicine.medical_treatment Catheter ablation Motor Activity Fluid-attenuated inversion recovery Air embolism Cardiac Catheters Gross examination Dogs Physiology (medical) Catheterization Peripheral medicine Animals Embolism Air Vertebral Artery Neurologic Examination Behavior Animal medicine.diagnostic_test business.industry Equipment Design medicine.disease Cerebral Angiography Disease Models Animal Diffusion Magnetic Resonance Imaging Intracranial Embolism Embolism Catheter Ablation Histopathology Radiology Cardiology and Cardiovascular Medicine business Carotid Artery Internal Diffusion MRI Cerebral angiography |
| Zdroj: | Circulation: Arrhythmia and Electrophysiology. 6:23-30 |
| ISSN: | 1941-3084 1941-3149 |
| DOI: | 10.1161/circep.112.973461 |
| Popis: | Background— Asymptomatic cerebral lesions have been observed on diffusion weighted MRI (DWI) scans shortly after catheter ablation of atrial fibrillation, but the pathogenesis of these lesions is incompletely understood. Methods and Results— Twelve dogs underwent selective catheterization of the internal carotid or vertebral arteries. Either a microbubbled mixture of air (1.0–4.0 mL), blood, contrast, and saline (n=5), or heat-dried pulverized blood (particle size Conclusions— Cerebral embolization of air microbubbles or microparticulate debris that approximate the embolic sources from catheter ablation can create hyperintense DWI punctate lesions in a canine model. The location and size of the DWI/fluid attenuating inversion recovery lesions correlate with pathological findings. |
| Databáze: | OpenAIRE |
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