Effects of active sunscreen ingredient combinations on the topical penetration of the herbicide 2,4-dichlorophenoxyacetic acid
| Autor: | Adam R Pont, Roselyn M Wilson, Rhonda M. Brand, Anna R. Charron |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
0301 basic medicine
2 4-Dichlorophenoxyacetic acid Health Toxicology and Mutagenesis Transdermal penetration Administration Topical DEET 010501 environmental sciences Pharmacology Toxicology 01 natural sciences Absorption 03 medical and health sciences chemistry.chemical_compound Ingredient Mice Animals Drug Interactions Food science 0105 earth and related environmental sciences Transdermal Skin Active ingredient 030102 biochemistry & molecular biology Herbicides Public Health Environmental and Occupational Health Penetration (firestop) Octocrylene chemistry Insect Repellents 2 4-Dichlorophenoxyacetic Acid Sunscreening Agents |
| Zdroj: | Toxicology and industrial health. 19(1) |
| ISSN: | 0748-2337 |
| Popis: | Sunscreen use can reduce the incidence of certain skin cancers. However, a number of commercially available formulations have been shown to enhance the transdermal penetration of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). Most of the active ingredients used in these compounds can individually act as penetration enhancers. Commercial sunscreens frequently contain multiple active ingredients in order to provide broad sunscreen protection. The purpose of this study was therefore to examine the effect of these active ingredient combinations on the transdermal absorption of 2,4-D in vitro. All six of the combinations tested resulted in increased cumulative penetration ( P |
| Databáze: | OpenAIRE |
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