Idiopathic thrombocytopenic purpura following allogeneic bone marrow transplantation--treatment with anti-D immunoglobulin
Autor: | Gilliland Dg, Churchill Wh, Stephanie J. Lee, Joseph H. Antin, Konugres A |
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Rok vydání: | 1997 |
Předmět: |
Adult
Male Rho(D) Immune Globulin Immunoglobulin E immune system diseases hemic and lymphatic diseases Immunopathology medicine Humans Transplantation Homologous Bone Marrow Transplantation Autoimmune disease Transplantation Purpura Thrombocytopenic Idiopathic biology business.industry Hematology medicine.disease Thrombocytopenic purpura Tacrolimus medicine.anatomical_structure Immunology Injections Intravenous biology.protein Bone marrow Antibody Complication business |
Zdroj: | Bone marrow transplantation. 19(2) |
ISSN: | 0268-3369 |
Popis: | A 38-year-old man developed idiopathic thrombocytopenic purpura (ITP) 8 months following allogeneic BMT while being treated for cGVHD with corticosteroids and tacrolimus (FK506). He received two courses of high-dose intravenous immunoglobulin (IvIG) which resulted in transient improvement. A single dose of intravenous anti-D immunoglobulin induced a durable response. Anti-D immunoglobulin is better tolerated, less complicated to administer, and less expensive than a course of IvIG. |
Databáze: | OpenAIRE |
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