Comparative diagnostic value and therapeutic relevance of magnetic resonance imaging and bone marrow scintigraphy in patients with metastatic solid tumors of the axial skeleton
| Autor: | Stefan Högerle, Jan Thorsten Winterer, Mathias Langer, Ernst Moser, O. Schäfer, Carsten Altehoefer, Nadir Ghanem |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Axial skeleton Lung Neoplasms Appendicular skeleton medicine.medical_treatment Bone Neoplasms Breast Neoplasms Scintigraphy Sensitivity and Specificity Metastasis Predictive Value of Tests Risk Factors medicine Humans Radiology Nuclear Medicine and imaging Radionuclide Imaging Retrospective Studies medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Lipoma medicine.disease Prognosis Magnetic Resonance Imaging Radiation therapy Radiography stomatognathic diseases medicine.anatomical_structure Urinary Bladder Neoplasms Female Bone marrow business Nuclear medicine Bone Marrow Neoplasms |
| Zdroj: | European journal of radiology. 43(3) |
| ISSN: | 0720-048X |
| Popis: | Purpose: To evaluate the comparative impact of magnetic resonance imaging (MRI) and bone marrow scintigraphy (BMS) in bone marrow metastases of solid tumors. Methods: In 20 patients with solid tumors MRI of the axial skeleton and whole-body BMS were retrospectively reviewed. Detectability of metastases, extent of disease and therapeutic implications were assessed. Results: In 15/20 (75%) patients MRI and BMS concordantly revealed bone marrow metastases of the axial skeleton. In nine of these 15 patients (60%) MRI showed more metastases. Local radiotherapy or surgery was performed in seven of these cases (78%). BMS detected additional metastases of the appendicular skeleton in 8/15 (53%) patients. In 4/20 cases (20%) the imaging findings were discordant. In three patients with degenerative changes ( n =2) or lipoma ( n =1) BMS was false positive. In another patient BMS failed to detect metastases proven by MRI and clinical follow-up resulting in subsequent radiation therapy. One patient had normal bone marrow. Conclusion: MRI appears to be more sensitive and specific in the detection of bone marrow metastases in the axial skeleton and is of clinical importance for subsequent local therapy. |
| Databáze: | OpenAIRE |
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