Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

Autor:	Karsten Siems, Hannah Benson, Florenz Sasse, Gerald Dräger, Andreas Kirschning, Eike Kunst, Torsten Busch
Rok vydání:	2016
Předmět:	Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie Macrocyclic Compounds Stereochemistry Cancer cell lines Antineoplastic Agents Chemistry Techniques Synthetic 010402 general chemistry 01 natural sciences Biochemistry Olefins chemistry.chemical_compound Tonantzitlolone Cell Line Tumor Humans Physical and Theoretical Chemistry Cell Proliferation 010405 organic chemistry Chemistry Organic Chemistry 0104 chemical sciences Cell culture ddc:540 Diterpene Diterpenes Anti-proliferative activities
Zdroj:	Organic and Biomolecular Chemistry 14 (2016), Nr. 38
ISSN:	1477-0539
Popis:	The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines. © The Royal Society of Chemistry 2016.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba626ba297620109e2c09946fb16844 https://pubmed.ncbi.nlm.nih.gov/27604289 Zobrazit plný text záznamu