Long-term functional sequelae of sacrococcygeal teratoma

Autor: L. W. Ernest van Heurn, Frans H. J. M. van der Staak, Joep P. M. Derikx, Nicolaas M.A. Bax, Antoine De Backer, Zacharias J. de Langen, Daniel C. Aronson, Léon van de Schoot, Thelma L. van den Hoonaard
Přispěvatelé: Pediatric Surgery, Surgery Specializations, Algemene Heelkunde, RS: NUTRIM School of Nutrition and Translational Research in Metabolism, RS: NUTRIM - R2 - Gut-liver homeostasis, RS: NUTRIM - R1 - Metabolic Syndrome, Paediatric Surgery, Other Research
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Male
bowel function
Pediatrics
Constipation
Urinary incontinence
Soft Tissue Neoplasms
CHILDREN
long-term results
sacrococcygeal teratoma
Postoperative Complications
Quality of life
Risk Factors
Surveys and Questionnaires
Survivors
Child
Cancer
Netherlands
Pelvic Neoplasms
Univariate analysis
urinary incontinence
Incidence (epidemiology)
Incidence
Teratoma
General Medicine
sequelae
Treatment Outcome
Child
Preschool
Female
medicine.symptom
Adult
medicine.medical_specialty
long-term sequelae
Adolescent
Esthetics
Cicatrix
Interventional oncology [UMCN 1.5]
medicine
yolk sac tumor
Humans
Retrospective Studies
business.industry
Sacrococcygeal Region
germ cell tumor
Odds ratio
medicine.disease
Surgery
functional results
Pediatrics
Perinatology and Child Health
Quality of Life
Defecation
business
Sacrococcygeal teratoma
Fecal Incontinence
Zdroj: Journal of Pediatric Surgery, 42(6), 1122-1126. W B SAUNDERS CO-ELSEVIER INC
Journal of Pediatric Surgery, 42(6), 1122-1126. W.B. Saunders
Journal of Pediatric Surgery, 42, 1122-6
Journal of Pediatric Surgery, 42, 6, pp. 1122-6
Journal of Pediatric Surgery, 42(6), 1122-1126. W B Saunders Co-Elsevier Inc
Journal of pediatric surgery, 42(6), 1122-1126. W.B. Saunders Ltd
ISSN: 0022-3468
Popis: Contains fulltext : 53285.pdf (Publisher’s version ) (Closed access) BACKGROUND: Long-term functional sequelae after resection of sacrococcygeal teratoma (SCT) are relatively common. This study determines the incidence of these sequelae associated clinical variables and its impact on quality of life (QoL). PATIENTS AND METHODS: Patients with SCT treated from 1980 to 2003 at the pediatric surgical centers in The Netherlands aged more than 3 years received age-specific questionnaires, which assessed parameters reflecting bowel function (involuntary bowel movements, soiling, constipation), urinary incontinence, subjective aspect of the scar, and QoL. These parameters were correlated with clinical variables, which were extracted from the medical records. Risk factors were identified using univariate analysis. RESULTS: Of the 99 posted questionnaires, 79 (80%) were completed. The median age of the patients was 9.7 years (range, 3.2-22.6 years). There were 46% who reported impaired bowel function and/or urinary incontinence (9% involuntary bowel movements, 13% soiling, 17% constipation), and 31% urinary incontinence. In 40%, the scar was cosmetically unacceptable. Age at completion of the questionnaire, Altman classification, sex, and histopathology were not risk factors for any long-term sequelae. Size of the tumor (>500 cm3) was a significant risk factor for cosmetically unacceptable scar (odds ration [OR], 4.73; confidence limit [CL], 1.21-18.47; P = .026). Long-term sequelae were correlated with diminished QoL. CONCLUSION: A large proportion of the patients with SCT have problems with defecation, urinary incontinence, or a cosmetically unacceptable scar that affects QoL. Patients who are at higher risk for the development of long-term sequelae cannot be clearly assessed using clinical variables.
Databáze: OpenAIRE
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