Survival study and factors associated with mortality in Chilean patients on peritoneal dialysis infected with SARS-CoV-2

Autor: Ana M Ortiz, Rodrigo A Sepúlveda, Rubén Torres, René Clavero, Luis Toro, Miguel Albornoz, Tatiana Aldunate, Ingrid Arce, Juan Arévalo, Andrés Arriagada, Julieta Becker, Sonia C González, Waldo Bernales, Eduardo Briones, Álvaro Castillo, Agustín Fuentes, Esteban Gómez, Hernán Jaramillo, Mario Lillo, Eduardo Lorca, Eduardo Machuca, Rodrigo Mansilla, Serwin Menéndez, Carlos Moya, Carolina Muñoz, William Neilson, Rodrigo Orozco, María Padrino, Edgard Pais, Gonzalo Ramírez, María E Sanhueza, Herman Schneider, Ruth Solís, Jaime Troncoso, Marcela Ursu, Marcela Valenzuela
Rok vydání: 2022
Předmět:
Zdroj: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 42(5)
ISSN: 1718-4304
Popis: The Covid-19 pandemic has been responsible for millions of deaths worldwide. Patients with comorbidities– such as those on peritoneal dialysis (PD)– present higher morbidity and mortality than the general population. We prospectively evaluated all Chilean patients on PD (48 centres) and followed those who had Covid-19 from the beginning of the Covid-19 pandemic in Chile (March 2020) to January 2021 (start of vaccination campaign). We described demographic history, comorbidities, factors related to infection, need for hospitalisation and death due to Covid-19. During the study period, 106 adults on PD were infected by SARS-CoV-2, with a mean age of 53.1 (±16.3) and of which 53.9% were female. From that group, 54.8% required hospitalisation and 24.5% ( n = 26) died due to Covid-19. Most of the patients (63.4%) were infected at home and 22.8% during hospitalisation for other reasons. There was a significant association for Covid-19 mortality with: being ≥60 years old, diabetes, time on PD ≥5 years, need for hospitalisation and hospital-acquired infection. At 90 days of follow-up, all deaths associated to Covid-19 occurred before 40 days. We conclude that patients on PD without Covid-19 vaccination have a high mortality and need for hospitalisation associated to Covid-19. To avoid this negative outcome, it is necessary to intensify strategies to avoid contagion, especially in those ≥60 years old, with diabetes and/or ≥5 years spent on PD.
Databáze: OpenAIRE