Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients

Autor: Kashif Bin Naeem, Mahmood Y. Hachim, Rajesh Quadros, Suad Hannawi, Haifa Hannawi, Ibrahim Y. Hachim, Ayman Chkhis, Fahdah Alokaily, Issa Al Salmi
Rok vydání: 2020
Předmět:
Adult
Male
cardiac injury
Corona virus
medicine.medical_specialty
medicine.medical_treatment
Pneumonia
Viral
Population
Saudi Arabia
Comorbidity
030204 cardiovascular system & hematology
Severity of Illness Index
Cohort Studies
03 medical and health sciences
Hospitals
Urban
0302 clinical medicine
Cause of Death
Internal medicine
Intensive care
medicine
Humans
Hospital Mortality
030212 general & internal medicine
education
Pandemics
Survival rate
Aged
Retrospective Studies
Cause of death
Mechanical ventilation
education.field_of_study
Septic shock
business.industry
Acute kidney injury
COVID-19
Retrospective cohort study
General Medicine
Middle Aged
acute respiratory distress syndrome
medicine.disease
mortality
Hospitalization
Survival Rate
Heart Injuries
Acute Disease
Female
Original Article
Coronavirus Infections
business
Zdroj: Saudi Medical Journal
ISSN: 1658-3175
0379-5284
DOI: 10.15537/smj.2020.11.25466
Popis: Objectives : To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population. Methods : A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury. Results : During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death. Conclusion : Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multi-organ damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended. Saudi Med J 2020; Vol. 41 (11): 1204-1210 doi: 10.15537/smj.2020.11.25466 How to cite this article: Naeem KB, Hachim MY, Hachim IY, Chkhis A, Quadros R, Hannawi H, Al Salmi I, Alokaily F, Hannawi S. Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients. A single-center experience. Saudi Med J. 2020 Nov;41(11):1204-1210. doi: 10.15537/smj.2020.11.25466.
Databáze: OpenAIRE
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