Tumour thrombus consistency has no impact on survival in patients with renal cell carcinoma
| Autor: | Jakub Bukowczan, Łukasz Curyło, Katarzyna Gołąbek, Robert Sobczyński, Tomasz Gołąbek, Krzysztof Okoń, Mikolaj Przydacz, Janusz Kopczyński, Jerzy Sadowski, Piotr Chlosta |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Oncology
Adult Male medicine.medical_specialty Tumour thrombus medicine.medical_treatment Kaplan-Meier Estimate Pathology and Forensic Medicine Consistency (statistics) Renal cell carcinoma Internal medicine medicine Overall survival Humans In patient cardiovascular diseases Thrombus Carcinoma Renal Cell Aged Retrospective Studies Aged 80 and over Venous Thrombosis business.industry General Medicine Middle Aged medicine.disease Prognosis Nephrectomy Kidney Neoplasms Cohort cardiovascular system Female Radiology business circulatory and respiratory physiology |
| Zdroj: | Polish journal of pathology : official journal of the Polish Society of Pathologists. 67(2) |
| ISSN: | 1233-9687 |
| Popis: | The prognosis of renal cell carcinoma (RCC) with venous tumour thrombus (VTT) is variable and not always possible to predict. The prognostic impact and independence of tumour thrombus-related factors including the recently introduced tumour thrombus consistency (TTC) on overall survival remain controversial. The aim of this study was to investigate the prognostic role of TTC in patients' survival. We determined the tumour thrombus consistency (solid vs. friable) in a cohort of 84 patients with RCC and VTT who underwent nephrectomy with thrombectomy, and performed a retrospective evaluation of the patients' data from the prospectively maintained database. A total of 45% of patients had solid thrombus (sTT) and 55% had friable thrombus (fTT). The venous tumour thrombus consistency was not predictive of overall survival. Further studies, preferably prospective and with a larger number of patients, are needed to validate the obtained results, as well as to evaluate the usefulness of tumour thrombus consistency in clinical practice for stratifying the risk of recurrence and planning further follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|