Acute toxicity of binary mixtures: alternative methods, QSAR and mechanisms

Autor:	Adéla Pokorná, Iveta Hanzlíková, Marián Rucki, Jana Tumová, Rút Uzlová, Miloň Tichý
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	Pharmacology Alternative methods Quantitative structure–activity relationship Operations research business.industry Health Toxicology and Mutagenesis Pharmacology toxicology Authorization Toxicology Acute toxicity Chemical safety Topical Essay Medicine Biochemical engineering business
Zdroj:	Interdisciplinary Toxicology
ISSN:	1337-9569 1337-6853
Popis:	Committee accepted the program of chemical safety in October 2003 called REACH, meaning “Registration, Evaluation, Authorization of Chemicals”. The protection of health of nature, including human beings, against harmful effects of chemicals is a goal of these programs. The development and research on new chemicals can become, however, cheaper than their testing and registration. The aim of effort of the present is, thus, to develop and to use alternative methods of testing toxic and adverse effects of chemicals, which would be cheaper and more informative than traditional tests with experimental animals.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b89dc6e43ee87667887c5e86a1476ef http://europepmc.org/articles/PMC2993475 Zobrazit plný text záznamu