Pharmacist Interventions for Prophylactic Antibiotic Use in Urological Inpatients Undergoing Clean or Clean-Contaminated Operations in a Chinese Hospital

Autor: Xin Li, Jin Ping Zhang, Wei Hong Ge, Hai-Xia Zhang, Hai Qin Huo, Pei Liang
Rok vydání: 2014
Předmět:
Bacterial Diseases
Male
Non-Clinical Medicine
Economics
Health Care Providers
Cost-Benefit Analysis
Health Care Sector
lcsh:Medicine
Social and Behavioral Sciences
Pharmacists
Urologic Surgical Procedure
Cost Effectiveness
Science Policy and Economics
Medicine
Prospective Studies
Antibiotic prophylaxis
lcsh:Science
health care economics and organizations
Pharmacist intervention
Allied Health Care Professionals
Multidisciplinary
Cost–benefit analysis
Clinical Pharmacology
Middle Aged
Socioeconomic Aspects of Health
Hospitals
Pharmacoeconomics
Infectious Diseases
Urologic Surgical Procedures
Female
Public Health
Research Article
Surgical patients
Prophylactic antibiotic
Drugs and Devices
medicine.medical_specialty
Clinical Research Design
Science Policy
Urology
Health Economics
Adverse Reactions
Humans
Health Care Quality
Retrospective Studies
Preventive healthcare
Urologic Infections
Inpatients
Health Care Policy
business.industry
lcsh:R
Retrospective cohort study
Communication in Health Care
Drug Policy
Antibiotic Prophylaxis
Surgery
Emergency medicine
lcsh:Q
business
Zdroj: PLoS ONE, Vol 9, Iss 2, p e88971 (2014)
PLoS ONE
ISSN: 1932-6203
Popis: OBJECTIVES: To evaluate the impact and cost-benefit value of pharmacist interventions for prophylactic antibiotic use in surgical patients undergoing clean or clean-contaminated operations. METHODS: A pre-to-post intervention study was performed in the Department of Urological Surgery of a tertiary hospital. Patients admitted from January through June 2011, undergoing clean or clean-contaminated surgery, served as the pre-intervention group; patients admitted from January through June 2012 formed the post-intervention group. Pharmacist interventions were performed for the surgeries in the post-intervention group. The criteria for the rational use of antibiotic prophylaxis were established by the hospital administration. The pharmacist interventions included real-time monitoring of medical records and controlling of the prescriptions of prophylactic antibiotics against the criteria. The pre- and post-intervention groups were then compared to evaluate the outcomes of the pharmacist interventions. A cost-benefit analysis was performed to determine the economic effects of implementing the pharmacist intervention on preoperative antibiotic prophylaxis. RESULTS: After the pharmacist intervention, a significant decrease was found in the rate of no indications for prophylactic antibiotic use (p = 0.004), the rate of broad-spectrum antibiotic use (p
Databáze: OpenAIRE
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