Spontaneous preterm delivery in the type 1 diabetic pregnancy: the role of glycemic control
| Autor: | Mark C. Chames, Oormila Kovilam, Bahaeddine M Sibai, Joseph A. Spinnato, Jane Khoury, Menachem Miodovnik |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
medicine.medical_specialty Pediatrics Pregnancy in Diabetics Logistic regression Obstetric Labor Premature Pregnancy Risk Factors Statistical significance medicine Humans Hypoglycemic Agents Insulin Preterm delivery Glycemic Glycated Hemoglobin Type 1 diabetes Obstetrics business.industry Poor glycemic control Infant Newborn Pregnancy Outcome Obstetrics and Gynecology medicine.disease Diabetes Mellitus Type 1 Hyperglycemia Pediatrics Perinatology and Child Health Female business Diabetic pregnancy |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 11:245-248 |
| ISSN: | 1476-4954 1476-7058 |
| Popis: | To determine the role of glycemic control in spontaneous preterm delivery in type 1 diabetic women.A secondary analysis of data from women enrolled in the Diabetes in Pregnancy Program prior to 20 weeks was performed. Multiple logistic regression was used to analyze the association between glycohemoglobin A1 in women with spontaneous preterm delivery (n = 53) and women who delivered at term (n = 200). Maternal demographics and obstetric outcomes were also compared between the groups.Glycohemoglobin A1 levels were higher in the spontaneous preterm delivery group than the term group throughout pregnancy, reaching statistical significance after the first trimester. The last glycohemoglobin A1 prior to delivery was 8.1% in the spontaneous preterm delivery group and 7.4% in the term group (p = 0.002). Using multiple logistic regression, each 1% increase in glycohemoglobin A1 increased the risk of spontaneous preterm delivery by 37%.Poor glycemic control is associated with an increased risk of spontaneous preterm delivery, suggesting that strict glycemic control may reduce the rate of preterm delivery in these women. |
| Databáze: | OpenAIRE |
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