Early predictors of short term neurodevelopmental outcome in asphyxiated cooled infants. A combined brain amplitude integrated electroencephalography and near infrared spectroscopy study
| Autor: | Francesca Sbravati, Giacomo Faldella, Eugenia Maranella, Silvia Savini, Elena Coccolini, Sara Grandi, Gina Ancora |
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| Přispěvatelé: | Ancora G., Maranella E., Grandi S., Sbravati F., Coccolini E., Savini S., Faldella G. |
| Rok vydání: | 2013 |
| Předmět: |
Encephalopathy
Hypoxic Ischemic Encephalopathy Cerebral palsy Developmental Neuroscience Hypothermia Induced Brain Cooling Humans Medicine Prospective Studies Prospective cohort study Asphyxia Neonatorum Spectroscopy Near-Infrared business.industry Infant Newborn Brain Electroencephalography General Medicine Hypothermia Prognosis medicine.disease Amplitude integrated electroencephalography Treatment Outcome Tissue oxygenation index Cerebral hemodynamics Anesthesia Hypoxia-Ischemia Brain Pediatrics Perinatology and Child Health Neurology (clinical) medicine.symptom business |
| Zdroj: | Brain and Development. 35:26-31 |
| ISSN: | 0387-7604 |
| DOI: | 10.1016/j.braindev.2011.09.008 |
| Popis: | Background: Brain Cooling (BC) represents the elective treatment in asphyxiated newborns. Amplitude Integrated Electroencephalography (aEEG) and Near Infrared Spectroscopy (NIRS) monitoring may help to evaluate changes in cerebral electrical activity and cerebral hemodynamics during hypothermia. Objectives: To evaluate the prognostic value of aEEG time course and NIRS data in asphyxiated cooled infants. Methods: Twelve term neonates admitted to our NICU with moderate-severe Hypoxic-Ischemic Encephalopathy (HIE) underwent selective BC. aEEG and NIRS monitoring were started as soon as possible and maintained during the whole hypothermic treatment. Follow-up was scheduled at regular intervals; adverse outcome was defined as death, cerebral palsy (CP) or global quotient |
| Databáze: | OpenAIRE |
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