Analysis of the Factors Affecting Survival in the Patients who Underwent Curative-Intent Gastrectomy due to Gastric Adenocarcinoma
| Autor: | Osman Nuri Dilek, Oguzhan Ozsay, Fevzi Cengiz, Emine Özlem Gür, Yasin Peker, Ahmet Er, Serkan Karaisli, Murat Kemal Atahan, Mehmet Haciyanli |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment overall survival Splenectomy Gastroenterology splenectomy Metastasis 03 medical and health sciences Gastric adenocarcinoma 0302 clinical medicine Internal medicine medicine Stage (cooking) prognostic factor Original Research business.industry Medical record Cancer General Medicine medicine.disease Splenic Hilum 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Gastrectomy gastric adenocarcinoma business Curative-intent gastrectomy |
| Zdroj: | The Medical Bulletin of Sisli Etfal Hospital |
| ISSN: | 1302-7123 |
| Popis: | Objectives Gastric cancer is the fifth most common cancer and the third most common cause of cancer-related deaths in the world. In this study, we aimed to evaluate the impact of clinicopathological factors on overall survival in the patients who underwent curative-intent gastrectomy due to gastric adenocarcinoma. Methods The medical records of 644 patients who underwent gastrectomy between January 2007 and January 2017 in our clinic were retrospectively reviewed. Among these patients, 359 patients were included in this study. The impact of several prognostic factors on survival was investigated. Results The mean age was 59.2±11.6 (29-83). Male/female ratio was 2.12. The median follow-up time was 19 months (CI=10.1-31.1). Median overall survival was 23±2.3 months (CI=18.3-27.6). Splenectomy, R1 (microscopically incomplete) resection, and advanced stage were independent risk factors for poor prognosis. Conclusion R1 resection, splenectomy, and advanced TNM stage were associated with poor prognosis in gastric cancer. Splenectomy should be avoided in the absence of direct invasion of the tumour or metastasis of lymph nodes on splenic hilum to prevent postoperative infectious complication-related mortality. |
| Databáze: | OpenAIRE |
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