Risk factors for late HIV diagnosis in the East of England: evidence from national surveillance data and policy implications
| Autor: | Lynsey Emmett, Neville Q. Verlander, Mark Reacher, Rachel E Bath |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Delayed Diagnosis Surveillance data Adolescent Databases Factual Sexual Behavior HIV diagnosis Human immunodeficiency virus (HIV) HIV Infections Dermatology medicine.disease_cause 03 medical and health sciences Age Distribution 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Risk Factors Epidemiology medicine Humans Pharmacology (medical) 030212 general & internal medicine Sex Distribution Medical diagnosis Heterosexuality Aged 030505 public health business.industry Public Health Environmental and Occupational Health Middle Aged medicine.disease Antiretroviral therapy CD4 Lymphocyte Count Infectious Diseases England Population Surveillance Family medicine Female Hiv status 0305 other medical science business |
| Zdroj: | International Journal of STD & AIDS. 30:37-44 |
| ISSN: | 1758-1052 0956-4624 |
| Popis: | In 2014, 42% of all HIV diagnoses in the East of England were diagnosed late. Individuals unaware of their HIV status will not benefit from lifesaving and infectious-limiting antiretroviral therapy, and they remain at risk of decreased life expectancy and onward transmission of HIV. We sought to identify risk factors associated with late HIV diagnosis in the East of England to inform future HIV testing and prevention strategies relevant to the local population. Data on all HIV infected individuals aged ≥16 years and diagnosed between 2008 and 2014 in the East of England were obtained from the national HIV and AIDS Reporting System. Late diagnosis was defined as CD4 cell count below 350 cells/mm3 within 91 days of diagnosis. Logistic regression investigated risk factors for late HIV diagnosis. A total of 2469 people were included; 1342 (54%) were late HIV diagnoses. In multivariable analysis risk factors for late diagnosis were: age ≥30 years, originating from WHO regions of South-East Asia or Europe (excluding UK), heterosexual orientation and being diagnosed as an inpatient or by a general practitioner. The odds of late diagnosis significantly reduced every year (OR 0.95, 95% CI 0.90–0.99, p = 0.042). Despite this year-on-year reduction continued high rates suggest future HIV testing and prevention strategies should be informed by local regional epidemiology to allow those at greatest risk to be targeted appropriately. |
| Databáze: | OpenAIRE |
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