Ultrasound and its clinical use in rheumatoid arthritis: where do we stand?
| Autor: | João Eurico Fonseca, Joaquim Polido-Pereira, Aline Defaveri do Prado, Henrique Luiz Staub, Inês Guimarães da Silveira, Melissa Cláudia Bisi, José Alexandre Mendonça |
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| Rok vydání: | 2018 |
| Předmět: |
lcsh:Immunologic diseases. Allergy
0301 basic medicine medicine.medical_specialty lcsh:Diseases of the musculoskeletal system Physical examination Musculoskeletal ultrasound Gray-scale Arthritis Rheumatoid 03 medical and health sciences Power doppler 0302 clinical medicine Rheumatology Internal medicine Synovitis Humans Medicine Patient Reported Outcome Measures Rheumatoid arthritis Physical Examination Ultrasonography Observer Variation 030203 arthritis & rheumatology medicine.diagnostic_test business.industry Power Doppler Ultrasound medicine.disease 030104 developmental biology Clinical research Physical therapy Cytokines lcsh:RC925-935 lcsh:RC581-607 business |
| Zdroj: | Advances in Rheumatology, Vol 58, Iss 1, Pp 1-10 (2018) |
| ISSN: | 2523-3106 |
| DOI: | 10.1186/s42358-018-0023-y |
| Popis: | High-resolution musculoskeletal ultrasound (MSUS) has been increasingly employed in daily rheumatological practice and in clinical research. In rheumatoid arthritis (RA), MSUS can be now considered a complement to physical examination. This method evaluates synovitis through gray-scale and power Doppler and it is also able to identify bone erosions. The utilization of MSUS as a marker of RA activity has received attention in recent literature. Current data account for good correlation of MSUS with classical measures of clinical activity; in some instances, MSUS appears to perform even better. Diagnosis of subclinical synovitis by MSUS might help the physician in RA management. With some variation, interobserver MSUS agreement seems excellent for erosion and good for synovitis. However, lack of MSUS score standardization is still an unmet need. In this review, we describe several MSUS scores, as well as their correlation with clinical RA activity and response to therapy. Finally, we look at the relationship of MSUS with synovial tissue inflammation and discuss future perspectives for a better interpretation and integration of this imaging method into clinical practice. |
| Databáze: | OpenAIRE |
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