Factors associated with increased suicidality risk following referral for isotretinoin commencement
| Autor: | Christopher Schofield, Vassiliki Tzanetakou, Andreas S Lappas, Lori Edwards Suarez, Nikos G. Christodoulou, Sally C. Morton |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Referral business.industry Psychiatric assessment medicine.disease Suicidal Ideation Suicide 030207 dermatology & venereal diseases 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Risk Factors medicine Humans Female 030212 general & internal medicine Isotretinoin skin and connective tissue diseases business Referral and Consultation Acne Retrospective Studies medicine.drug |
| Zdroj: | Australasian Psychiatry. 30:44-48 |
| ISSN: | 1440-1665 1039-8562 |
| Popis: | Objective: To establish whether there is a significant change in suicidality risk following psychiatric assessment for commencement of isotretinoin and identify factors that underpin any potential risk change. Method: Retrospective cohort study. Suicidality risk was defined as a combination of the following: (i) actual/intended self-harm and/or attempted/completed suicide, and (ii) increased service utilisation associated with suicidal ideation/behaviour. All patients referred to Psychiatry for assessment prior to commencement of isotretinoin between 2014 and 2019 were examined. Inclusion criteria: >16 years of age, assessed for commencement of isotretinoin, complete clinical records. Data were collected by reviewing the Electronic Patient Records. Fifty-seven patients were eligible. We employed descriptive statistics, parametric/non-parametric/normality tests and logistic regression analysis, using socio-demographic and clinical characteristics as independent parameters, and suicidality risk as the dependent parameter. Results: Actual/intended self-harm/attempted suicide decreased significantly following assessment without significant change in service utilisation. Female gender, absence of protective factors and assessment by Consultation-Liaison Psychiatry were linked to increased suicidality risk, after controlling for age, ethnicity, recommendation for isotretinoin, and substance misuse. Conclusions: Psychiatric assessment is helpful before commencing isotretinoin. Female gender, and absence of ongoing psychopharmacological and/or psychological intervention and/or regular psychiatric follow-up predict increased suicidality risk among patients assessed for prescription of isotretinoin. |
| Databáze: | OpenAIRE |
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