The influence of hospital‐based intravenous immunoglobulin and home‐based self‐administrated subcutaneous immunoglobulin therapy in young children with primary immunodeficiency diseases on their parents’ / caregivers’ satisfaction
| Autor: | Agnieszka Sobocińska, Joanna Jerzyńska, Joanna Lechanska‐Helman, Iwona Stelmach |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Parents Pediatrics medicine.medical_specialty Primary Immunodeficiency Diseases Self Administration Personal Satisfaction Disease 030204 cardiovascular system & hematology Subcutaneous immunoglobulin Infusions Subcutaneous 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires 030225 pediatrics Humans Immunologic Factors Medicine IVIG Therapy biology business.industry Immunologic Deficiency Syndromes Immunoglobulins Intravenous Infant Hospital based medicine.disease Home based Hospitals Caregivers Child Preschool Immunoglobulin G Pediatrics Perinatology and Child Health Quality of Life biology.protein Primary immunodeficiency Anxiety Female Poland Antibody medicine.symptom business Attitude to Health |
| Zdroj: | Pediatrics International. 62:316-318 |
| ISSN: | 1442-200X 1328-8067 |
| DOI: | 10.1111/ped.14119 |
| Popis: | Background Immunoglobulin replacement has been standard therapy for patients with primary immunodeficiency diseases (PIDD). Intravenous immunoglobin (IVIg) is delivered at the hospital, whereas subcutaneous immunoglobin (SCIg) is used for home-based treatment. The aim of the study was to determine the advantages and disadvantages of IVIg and SCIg in Polish children aged 1-5 years, with PIDD, and the satisfaction of their parents / caregivers regarding immunoglobulin replacement. Methods The research involved parents of 23 children with PIDD, aged 1-5 years. All children were given IVIg therapy and after at least 6 months they were switched towards home SCIg therapy for at least 6 months. A questionnaire assessing advantages and disadvantages of preferred types of treatment and the quality of life of PIDD patients' families' lives was used. Results The research showed that IVIg therapy was better accepted by parents than SCIg therapy (P = 0.034) for the following reasons: It made it possible for the children to receive treatment once per month (60%); it reduced the fear of injecting the children (60%), and it provided better control of the disease through regular visits to the hospital (53.33%). Parents noticed, however, that IVIg had a significant impact on absence at school or work (70%). Parents who preferred SCIg for their children were guided mainly by the smaller number of side effects (40%), and the fact that the treatment did not interfere with parents' work or the children's school (40%). Conclusion The results showed that IVIg therapy was better accepted by parents than SCIg therapy Parents of children with SCIg are less satisfied with their life, and feel anxiety about their children disease, which is related to administering the medicine by themselves. |
| Databáze: | OpenAIRE |
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