Effects of etomidate on bispectral index scale and spectral entropy during induction of anesthesia by means of the raw electroencephalographic and electromyographic characteristics
| Autor: | Ji-Young Yoon, Sang-Wook Shin, Hyeon Jeong Lee, Kyung-Hoon Kim, Seong-Wan Baik, Hyun-Mok Kim |
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| Rok vydání: | 2011 |
| Předmět: |
Myoclonus
Clinical Research Article medicine.drug_class business.industry Bispectral index scale Electromyography Spectral entropy medicine.medical_treatment Entropy Sevoflurane Hypnotic lcsh:RD78.3-87.3 Anesthesiology and Pain Medicine Etomidate lcsh:Anesthesiology Anesthesia Bispectral index medicine Intubation Rocuronium medicine.symptom business medicine.drug |
| Zdroj: | Korean Journal of Anesthesiology Korean Journal of Anesthesiology, Vol 62, Iss 3, Pp 230-233 (2012) |
| ISSN: | 2005-7563 |
| Popis: | BACKGROUND: Etomidate frequently induces myoclonus, so it may affect electromyographics (EMG). And EMG commonly has an effect on the bispectral index scale (BIS) and spectral entropy. This study was performed to compare the effect of etomidate on BIS, response entropy (RE) and state entropy (SE) during induction of anesthesia. METHODS: Fifty patients (ASA I or II) scheduled for elective surgery were included in this study. Anesthesia was induced with etomidate (0.3 mg/kg) and rocuronium (0.6 mg/kg). Patients also inhaled 4 vol% sevoflurane and 100% oxygen and, then intubated. BIS, RE, SE and Modified Observer's Assessment of Alertness/Sedation Scale (MOAA/S) were measured 4 times (before injection of etomidate [T0], at loss of eyelash reflex [T1], 90 seconds after rocuronium injection [T2], and after intubation [T3]). We also checked whether myoclonus occurred. RESULTS: Baseline values (T0) were 93.1 ± 4.7 for BIS, 95.8 ± 3.7 for RE and, 87.3 ± 3.5 for SE. In comparison with T0, there were significantly differences in BIS (50.2 ± 16.3), RE (76.8 ± 18.5) and SE (66.3 ± 17.4) at T1 (all P < 0.05). There were no significant differences at T2 and T3. Thirty one patients had myoclonus. At the occurrence of myoclonus, RE and SE values significantly increased but not BIS (P < 0.05). CONCLUSIONS: In patients with myoclonus, at the loss of consciousness, spectral entropy did not decrease where as BIS did, suggesting that BIS may evaluate hypnotic levels better than spectral entropy during induction of anesthesia with etomidate. |
| Databáze: | OpenAIRE |
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