Severe dengue associated withStaphylococcus aureussepsis in pediatric patients: a case series
| Autor: | K C Sudeep, Surjeet Kumar, Manjinder Singh Randhawa, Suresh Kumar Angurana, Karthi Nallasamy, Arun Bansal, Jayashree Muralidharan |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Tropical Pediatrics. 69 |
| ISSN: | 1465-3664 0142-6338 |
| DOI: | 10.1093/tropej/fmac102 |
| Popis: | BackgroundStaphylococcus aureus co-infection is seldom reported in children with severe dengue.MethodologyIn this retrospective study, we reported five children with severe dengue and S. aureus co-infection admitted to pediatric intensive care unit (PICU) during July–December 2021.ResultsAll children had prolonged fever, persistence of bilateral pleural effusion beyond the critical phase, thrombocytopenia and raised inflammatory markers [C-reactive protein (CRP) and procalcitonin]. S. aureus was isolated from pleural fluid (n = 2, 40%), blood (n = 2, 40%) and endotracheal aspirate (n = 1, 20%). Four children (80%) grew methicillin-sensitive S. aureus, while 1 (20%) had methicillin-resistant S. aureus. Two children (40%) had septic thromboemboli in skin, and 1 (20%) had limb cellulitis. One child required anterior thoracotomy, pericardiectomy and bilateral pleural decortication, while all other children required intercostal chest tube drainage. All children required prolonged targeted antibiotics, invasive mechanical ventilation and had prolong stay in PICU and all of them survived.ConclusionIn children with severe dengue, persistence of fever, persistence of pleural effusion beyond critical phase and raised CRP and procalcitonin should raise suspicion of bacterial/S. aureus co-infection. |
| Databáze: | OpenAIRE |
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