Glyceryl trinitrate vs. sphincterotomy for treatment of chronic fissure-in-ano
| Autor: | G. J. Oettlé |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Anorectal disease Administration Topical medicine.medical_treatment Chronic anal fissure Anal Canal Fissure in ano law.invention Ointments Nitroglycerin Randomized controlled trial law medicine Humans Aged Anal fissure business.industry Gastroenterology General Medicine Middle Aged medicine.disease Colorectal surgery Surgery Anesthesia Chronic Disease Female Fissure in Ano Lateral internal sphincterotomy business Follow-Up Studies |
| Zdroj: | Diseases of the Colon & Rectum. 40:1318-1320 |
| ISSN: | 0012-3706 |
| DOI: | 10.1007/bf02050816 |
| Popis: | PURPOSE: This study was undertaken to compare local application of a glyceryl trinitrate ointment with lateral internal sphincterotomy for the treatment of chronic fissure-in-ano. PATIENTS AND METHODS: A sample of 24 consecutive patients with chronic anal fissure was randomly allocated to treatment with sphincterotomy or local glyceryl trinitrate. Patients were followed-up for a median of 22 months. RESULTS: All 12 patients healed following sphincterotomy; 10 of 12 healed with local glyceryl trinitrate (P=0.239). There were no recurrences or side-effects in either group. CONCLUSIONS: Local application of glyceryl trinitrate can avoid surgery in more than 80 percent of patients with chronic anal fissure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink