Preliminary report on a cost-utility analysis of revascularization by percutaneous coronary intervention for ischemic heart disease

Autor: Tomoyuki Takura, Tadashi Kuroda, Isamu Mizote, Satoru Sumitsuji, Takaaki Isshiki, Shinsuke Nanto, Seiko Ide, Kouichi Tachibana
Rok vydání: 2016
Předmět:
Male
medicine.medical_specialty
Visual analogue scale
Cost-Benefit Analysis
medicine.medical_treatment
Coronary Artery Disease
Disease
030204 cardiovascular system & hematology
Coronary Angiography
Revascularization
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Japan
Quality of life
Surveys and Questionnaires
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging
030212 general & internal medicine
Aged
Retrospective Studies
Cost–utility analysis
business.industry
Reproducibility of Results
Percutaneous coronary intervention
Health Care Costs
General Medicine
Conventional PCI
Quality of Life
Physical therapy
Cardiology
Female
Quality-Adjusted Life Years
Cardiology and Cardiovascular Medicine
Ischemic heart
business
Follow-Up Studies
Zdroj: Cardiovascular Intervention and Therapeutics. 32:127-136
ISSN: 1868-4297
1868-4300
DOI: 10.1007/s12928-016-0401-5
Popis: Few socioeconomic studies have so far reported on revascularization for stable ischemic heart disease in Japan. This study aimed to validate the sensitivity of the health-related quality of life (HRQOL) scale for determining the pathology and medical technology to be used and to validate the application of a cost-utility analysis model. We studied 32 patients who had undergone percutaneous coronary intervention (PCI) (mean age 67.9 ± 7.3 years). For HRQOL, utility and quality of life (QOL) were examined using the EuroQol 5 Dimension (EQ-5D) and EuroQol Visual Analogue Scale (EQ-VAS), respectively. The changes in the utility index before and after PCI were compared between the PCI and coronary angiography (CAG) groups to determine the sensitivity of the EQ-5D that was used to calculate quality-adjusted life years (QALY). Additionally, to estimate the cost-utility of PCI 120 months after the procedure, we analyzed our study results and the results of previous reports using the Markov chain model. The utility index was found to improve in the PCI group (0.08 ± 0.15), whereas it decreased in the CAG group (-0.02 ± 0.11) (p = 0.049). The estimated result of the cost-utility analysis as the increase in utility above baseline level was the expected value, that is, 70,000 US$/QALY. Our findings suggest that QALY may be valid as a utility index in the clinical and economic evaluation of PCI in Japan.
Databáze: OpenAIRE
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