Immunologic Aspects of Otitis Media
Autor: | Tauno Palva, Jukka Ylikoski, V. Raunio, P. Hayry |
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Rok vydání: | 1980 |
Předmět: |
Pathology
medicine.medical_specialty Rosette Formation Granulocytic cells T-Lymphocytes Ear Middle Immunoglobulins Immune system Leukocytes Humans Immune Complex Diseases Medicine Lymphocytes Antigens Bacterial Immunity Cellular Mucous Membrane Staining and Labeling biology business.industry Esterases Proteins Mucous membrane Exudates and Transudates General Medicine Otitis Media medicine.anatomical_structure Otitis Otorhinolaryngology Effusion Rosette formation Immunology biology.protein Electrophoresis Polyacrylamide Gel Muramidase medicine.symptom Antibody business Immune complex disease |
Zdroj: | Acta Oto-Laryngologica. 89:177-181 |
ISSN: | 1651-2251 0001-6489 |
DOI: | 10.3109/00016488009127125 |
Popis: | The cellular immune response in otitis media with effusion consisted of granulocytic cells in the majority (60--70%) of cases, while the monocytic-lymphocytic cells formed the bulk of cells present in 20%. A considerable number (15--20%) of serous, seromucinous and mucoid effusions had sparse cellular populations. T-lymphocytes, marked with alpha-naphthyl-acetate-esterase (ANAE) constituted the majority of lymphocytes and were present in effusion liquids in numbers similar to those in blood. Tests with E-rosettes confirmed the results obtained with ANAE stain. The finding that T-lymphocytes are present in normal numbers may link the mucosal damage to the delayed-type hypersensitivity reaction. Another explanation of mucosal damage may be sought in immune complexes, which have recently been found to be present in many sterile middle ear liquids. |
Databáze: | OpenAIRE |
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