Saponinas antifúngicas de Swartzia langsdorffii
| Autor: | Luce Maria Brandão Torres, Luciana de Avila Santos, Ian Castro-Gamboa, Maria Claudia Marx Young, Vanderlan da Silva Bolzani, Maria José Soares Mendes-Giannini, Renata Brionízio Lemos, S. R. Marqui, Liliana Scorzoni, A. M. Fusco-Almeida, Alberto José Cavalheiro, Dulce Helena Siqueira Silva |
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| Přispěvatelé: | Instituto de Botânica, Universidade Estadual Paulista (Unesp) |
| Jazyk: | portugalština |
| Rok vydání: | 2008 |
| Předmět: |
Cryptococcus neoformans
Antifungal Traditional medicine biology Stereochemistry medicine.drug_class antifungal activity Cladosporium cladosporioides General Chemistry biology.organism_classification Swartzia langsdorffii carbohydrates (lipids) chemistry.chemical_compound chemistry saponins medicine Pentacyclic Triterpenes Candida albicans Spectral data Oleanolic acid Lupeol |
| Zdroj: | SciELO Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Química Nova v.31 n.4 2008 Química Nova Sociedade Brasileira de Química (SBQ) instacron:SBQ |
| ISSN: | 0100-4042 |
| Popis: | Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:48:42Z No. of bitstreams: 1 S0100-40422008000400023.pdf: 58223 bytes, checksum: db5304c6c8c19f2ec6fdff51d385edef (MD5) Made available in DSpace on 2013-08-22T18:48:42Z (GMT). No. of bitstreams: 1 S0100-40422008000400023.pdf: 58223 bytes, checksum: db5304c6c8c19f2ec6fdff51d385edef (MD5) Previous issue date: 2008-01-01 Made available in DSpace on 2013-09-30T18:07:06Z (GMT). No. of bitstreams: 2 S0100-40422008000400023.pdf: 58223 bytes, checksum: db5304c6c8c19f2ec6fdff51d385edef (MD5) S0100-40422008000400023.pdf.txt: 22629 bytes, checksum: 30be36f667437f7f3ee84ded2aa4e676 (MD5) Previous issue date: 2008-01-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:20:40Z No. of bitstreams: 2 S0100-40422008000400023.pdf: 58223 bytes, checksum: db5304c6c8c19f2ec6fdff51d385edef (MD5) S0100-40422008000400023.pdf.txt: 22629 bytes, checksum: 30be36f667437f7f3ee84ded2aa4e676 (MD5) Made available in DSpace on 2014-05-20T14:20:40Z (GMT). No. of bitstreams: 2 S0100-40422008000400023.pdf: 58223 bytes, checksum: db5304c6c8c19f2ec6fdff51d385edef (MD5) S0100-40422008000400023.pdf.txt: 22629 bytes, checksum: 30be36f667437f7f3ee84ded2aa4e676 (MD5) Previous issue date: 2008-01-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Chromatographic fractionation of the EtOH extract from the leaves of Swartzia langsdorffii afforded the pentacyclic triterpenes oleanolic acid and lupeol, and two saponins: oleanolic acid 3-sophoroside and the new ester 3-O-b-D-(6'-methyl)-glucopyranosyl-28-O-b-D-glucopyranosyl-oleanate. Their structures were elucidated from spectral data, including 2D NMR and HRESIMS experiments. Antifungal activity of all isolated compounds was evaluated, using phytopathogens Cladosporium cladosporioides and C. sphaerospermum, and human pathogens Candida albicans, C. krusei, C. parapsilosis and Cryptococcus neoformans. Universidade Estadual Paulista Instituto de Química Universidade Estadual Paulista Faculdade de Ciências Farmacêuticas Instituto de Botânica Seção de Fisiologia e Bioquímica de Plantas Universidade Estadual Paulista Instituto de Química Universidade Estadual Paulista Faculdade de Ciências Farmacêuticas FAPESP: 03/02176-7 FAPESP: 04/07932-7 |
| Databáze: | OpenAIRE |
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