Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
| Autor: | Karen B. Schaal, Zhongdi Chu, Sophie Kubach, Luiz Roisman, Giovanni Gregori, Mary K Durbin, Philip J. Rosenfeld, William J. Feuer, Fang Zheng, Paul F. Stetson, Chieh-Li Chen, Ruikang K. Wang, Qinqin Zhang, Lin An, João Rafael de Oliveira Dias, Andrew R. Miller, Zohar Yehoshua |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Visual acuity genetic structures Fundus Oculi Visual Acuity neovascular AMD Spectral domain optical coherence tomography angiography 01 natural sciences choroidal neovascularization Retina 010309 optics 03 medical and health sciences 0302 clinical medicine Optical coherence tomography 0103 physical sciences medicine Medical imaging Humans Prospective Studies Fluorescein Angiography swept-source OCTA Aged Aged 80 and over spectral-domain OCTA medicine.diagnostic_test Extramural business.industry Choroid Reproducibility of Results Optical coherence tomography angiography Middle Aged eye diseases Choroidal Neovascularization Choroidal neovascularization 030221 ophthalmology & optometry Female Tomography sense organs medicine.symptom Erratum Nuclear medicine business OCTA Tomography Optical Coherence |
| Zdroj: | Repositório Institucional da UNIFESP Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP Investigative Ophthalmology & Visual Science |
| Popis: | Carl Zeiss Meditec, Inc. National Eye Institute Research to Prevent Blindness, Inc. (New York, NY) National Eye Institute Center Core Grant CAPES Foundation, Ministry of Education of Brazil (Brasilia, Brazil) German Research Foundation PURPOSE. The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). METHODS. Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 x 3-and 6 x 6-mm(2) scans were obtained on both instruments. The 3 x 3-mm(2) SS-OCTA scans consisted of 300 A-scans per B-scan at 300 B-scan positions, and the SD-OCTA scans consisted of 245 A-scans at 245 B-scan positions. The 6 x 6-mm(2) SS-OCTA scans consisted of 420 A-scans per B-scan at 420 B-scan positions, and the SD-OCTA scans consisted of 350 A-scans and 350 B-scan positions. B-scans were repeated four times at each position in the 3 x 3-mm(2) scans and twice in the 6 x 6-mm(2) scans. Choroidal neovascularization was excluded if not fully contained within the 3 x 3-mm(2) scans. The same algorithm was used to detect CNV on both instruments. Two graders outlined the CNV, and the lesion areas were compared between instruments. RESULTS. Twenty-seven consecutive eyes from 23 patients were analyzed. For the 3 x 3-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.17 and 1.01 mm(2), respectively (P = 0.047). For the 6 x 6-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.24 and 0.74 mm(2) (P = 0.003). CONCLUSIONS. The areas of CNV tended to be larger when imaged with SS-OCTA than with SD-OCTA, and this difference was greater for the 6 x 6-mm(2) scans. Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA Univ Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil Univ Washington, Dept Bioengn, Seattle, WA 98195 USA Carl Zeiss Meditec Inc, Adv Dev, Dublin, CA USA Univ Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil National Eye Institute: R01EY024158 National Eye Institute Center Core Grant: P30EY014801 German Research Foundation: SCHA 1869/1-1 Web of Science |
| Databáze: | OpenAIRE |
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