Primary Pulmonary Synovial Sarcoma: A Case Report and Review of Current Diagnostic and Therapeutic Standards
Autor: | George Giacoppe, Eric Weppler, Sheri Dennison |
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Rok vydání: | 2004 |
Předmět: |
Adult
Cancer Research medicine.medical_specialty Lung Neoplasms Oncogene Proteins Fusion Chest pain Malignancy Translocation Genetic Sarcoma Synovial Primary Synovial Sarcoma Humans Medicine Young adult Survival rate Lung business.industry medicine.disease Immunohistochemistry Synovial sarcoma Surgery medicine.anatomical_structure Oncology Female Radiology Sarcoma medicine.symptom business |
Zdroj: | The Oncologist. 9:339-342 |
ISSN: | 1549-490X 1083-7159 |
DOI: | 10.1634/theoncologist.9-3-339 |
Popis: | Learning Objectives After completing this course, the reader will be able to: Describe primary pulmonary synovial sarcoma as a rare tumor that usually arises in young adults as a large pleural-based intrathoracic mass. Explain that the diagnosis is made by histology, immunohistochemical studies, and, more recently, by identification of the SYT-SSX1 or SYT-SSX2 chromosomal translocations. List factors that portend a worse prognosis, including inability to achieve a complete resection, larger tumor size, male sex, older age, high-grade tumor with necrosis, and the SYT-SSX1 variant. Access and take the CME test online and receive 1 hour of AMA PRA category 1 credit at CME.TheOncologist.com A 30-year-old female presented with hemoptysis, chest pain, and a rapidly enlarging pleural-based mass, and was found to have primary synovial sarcoma of the lung. Primary pulmonary sarcomas comprise |
Databáze: | OpenAIRE |
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