Ceftazidime in clinical practice
| Autor: | Kjell Alestig, J. E. Brorson, Ragnar Norrby, Birger Trollfors, Tönnes Eilard, R. Svensson |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Urinary system Ceftazidime medicine.disease_cause Thrombophlebitis Gastroenterology Microbiology chemistry.chemical_compound Sepsis Internal medicine medicine Humans Pharmacology (medical) Skin Diseases Infectious Respiratory Tract Infections Osteitis Aged Sweden Pharmacology Clinical Trials as Topic Creatinine Respiratory tract infections business.industry Bacterial Infections Middle Aged medicine.disease Cephalosporins Diarrhea Infectious Diseases chemistry Staphylococcus aureus Urinary Tract Infections Female Drug Eruptions medicine.symptom business medicine.drug |
| Zdroj: | Journal of Antimicrobial Chemotherapy. 12:111-114 |
| ISSN: | 1460-2091 0305-7453 |
| Popis: | In an open trial, the efficacy of intravenously administered ceftazidime was evaluated in 106 adult patients with urinary or respiratory tract infections, soft tissue infections, osteitis and septicaemia. The most commonly isolated pathogens were Escherichia coli, Pseudomonas spp. and Staphylococcus aureus. Of 85 organisms isolated before treatment, 79% were cleared and 15% were cleared but later relapsed often because of the underlying conditions. Clinical cure was achieved in 70%, improvement occurred in 25% of the patients and 6% failed to respond. Marked increases in serum creatinine occurred in three patients with pre-existing renal impairment treated with ceftazidime in unmodified dosage. Exanthema, diarrhoea or local thrombophlebitis was noted in 13 patients. |
| Databáze: | OpenAIRE |
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