Anterior circulation large vessel occlusion stroke in Saudi Arabia: Prevalence, predictors, and outcome
| Autor: | Bayan Al Bdah, M. Alskaini, Saeed A. Al-Ghamdi, Ali M. Al Khathaami, Mohammed A. Aldriweesh, Sultan A. Alsaif, Nasser Alotaibi, Muath A. Alhasson, Waleed A. Alluhidan, Faisal M. Almutairi |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Saudi Arabia Neuroimaging Comorbidity Tertiary care Brain Ischemia Disability Evaluation 03 medical and health sciences 0302 clinical medicine Reperfusion therapy Risk Factors Modified Rankin Scale Internal medicine Prevalence medicine Humans cardiovascular diseases Stroke Aged Retrospective Studies business.industry Rehabilitation Atrial fibrillation Emergency department Length of Stay Middle Aged Prognosis medicine.disease Cerebrovascular Circulation Ischemic stroke Cardiology Female Surgery Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Large vessel occlusion |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases. 29:105080 |
| ISSN: | 1052-3057 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2020.105080 |
| Popis: | Anterior circulation Large Vessel Occlusion (LVO) stroke comes with significant morbidity and mortality. With the advent of endovascular interventions, its management has revolutionized. For health authorities to build systems and allocate resources, its burden, predictors, and outcome must be determined.In a single tertiary care center, we retrospectively collected data from 1495 ischemic stroke patients to determine anterior circulation LVO prevalence, predictors, and outcome. Patients must have radiologically proven ischemic stroke within 24 hours before arrival at the emergency department. Anterior circulation LVO related stroke was defined as evidence of new anterior circulation infarct detected on neuroimaging, and vascular imaging confirming anterior circulation Large Vessel Occlusion. Data on demographics, vascular risk factors, treatment with reperfusion therapy, modified Rankin Scale (mRS) at admission, National Institute of Health Stroke Scale (NIHSS) at admission, length of stay (LOS) in days, and in-hospital comorbidities and death were collected. Regression analysis was done to determine the predictors and outcomes of anterior circulation LVO ischemic strokes.We found anterior circulation LVO in 27.8% (95 % CI 25.5-30.0) of all ischemic stroke patients. Atrial fibrillation and admission National Institute of Health Stroke Scale (NIHSS) were the strongest predictors of LVO [OR 2.33, P = 0.0011 and OR 1.17, P0.0001] respectively. Occurrence of LVO was associated with worse disability score (mRS ≥ 3) [47.22 vs. 19.81% (P = 0.0073)], longer hospitalization in days [Median 9.0 vs. 3.0, IQR (14.0 vs. 5.0) P = 0.0432)], and was more likely to results in patient admission to intensive care unit [Mean 17.59 vs. 3.70 % (P = 0.0002)].Stroke with large vessel occlusion in Saudi Arabia is not uncommon. Its burden and outcome deserve national attention, as effective treatment is now readily available. |
| Databáze: | OpenAIRE |
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