The neurobiological hypothesis of neurotrophins in the pathophysiology of schizophrenia: A meta-analysis
| Autor: | Carlos Spuch, María de Carmen Vallejo-Curto, Daniela Rodrigues-Amorim, João Bessa, Roberto Díaz, Tania Rivera-Baltanás, Roberto Carlos Agís-Balboa, María Elena de las Heras, José Manuel Olivares, Nuno Sousa, Cynthia Rodriguez-Jamardo |
|---|---|
| Přispěvatelé: | Universidade do Minho |
| Rok vydání: | 2018 |
| Předmět: |
Nervous system
Adult Male Medicina Básica [Ciências Médicas] Disease 03 medical and health sciences Young Adult 0302 clinical medicine Neurotrophic factors Neuroplasticity medicine Humans Nerve Growth Factors Biological Psychiatry Science & Technology biology business.industry Middle Aged medicine.disease Pathophysiology 3. Good health 030227 psychiatry Psychiatry and Mental health medicine.anatomical_structure Nerve growth factor nervous system Schizophrenia Ciências Médicas::Medicina Básica biology.protein Female business Neuroscience 030217 neurology & neurosurgery Neurotrophin |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| ISSN: | 1879-1379 |
| Popis: | Schizophrenia is associated with patterns of aberrant neurobiological circuitry. The disease complexity is mirrored by multiple biological interactions known to contribute to the disease pathology. One potential contributor is the family of neurotrophins which are proteins involved in multiple functional processes in the nervous system, with crucial roles in neurodevelopment, synaptogenesis and neuroplasticity. With these roles in mind, abnormal neurotrophin profiles have been hypothesized to contribute to the pathology of schizophrenia. CS is supported by the Fundación Tatiana Pérez de Guzman el Bueno and Rede Galega de Investigación en DemenciasIN607C-2017/02, GAIN, Xunta de Galicia, JMO is supported by ISCIIIP16/00405, RCAB is funded by FEDER, a Ramón& Cajal grant (RYC-2014-15246) and the Galicia Innovation Agency - GAIN grant (IN607D-2016/003) info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
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