Risk factors of primary and secondary restless legs syndrome among a middle-aged population in Saudi Arabia: A community-based study
| Autor: | Hanadi Sabbahi, Siraj O. Wali, Bedor Alotaiby, Bahaa Abaalkhail, Khaled Aljammali, Samah Alsafadi, Ibrahim Zakaria |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Population Community based study 03 medical and health sciences 0302 clinical medicine Rating scale Internal medicine mental disorders medicine 030212 general & internal medicine Restless legs syndrome Secondary restless legs syndrome education Male gender lcsh:RC705-779 education.field_of_study business.industry lcsh:Diseases of the respiratory system medicine.disease Aged population restless legs syndrome severity lcsh:RC666-701 Baseline characteristics restless legs syndrome Surgery Original Article Cardiology and Cardiovascular Medicine business secondary 030217 neurology & neurosurgery Primary |
| Zdroj: | Annals of Thoracic Medicine Annals of Thoracic Medicine, Vol 13, Iss 3, Pp 175-181 (2018) |
| ISSN: | 1998-3557 1817-1737 |
| Popis: | INTRODUCTION: Restless legs syndrome (RLS) is etiologically divided into primary and secondary syndromes. However, a comparative description of both types is lacking in the literature. We compared primary and secondary RLS with respect to demographic determinants, associated risk factors, and comorbidities. METHODS: Following a cross-sectional survey on the prevalence of RLS in a Saudi population, RLS cases were identified using the International RLS Study Group (IRLSSG) criteria. Cases were assessed with an interview-based questionnaire regarding baseline characteristics, risk factors, and comorbidities and with lower limb examinations and laboratory measurements. RLS severity was assessed using the IRLSSG Severity Rating Scale. RESULTS: In total, 78 patients with RLS, including 50 (64.1%) primary and 28 (35.9%) secondary cases, were examined. Of the primary cases, 35 (70%) were male; of the secondary cases, 25 (89.3%) were female (P < 0.001). Multivariate regression confirmed the association of male gender with primary RLS (odds ratio = 14.53, 95% confidence interval [2.9–75], P = 0.001). There were more dark- and black-skinned participants in the primary RLS group (38, 72%) than in the secondary group (15, 28%) (P = 0.042). Iron deficiency was observed in most (26, 92%) of the secondary cases. More severe symptoms were reported in secondary than in primary RLS cases (P < 0.05). CONCLUSIONS: Primary RLS is more common but less severe than secondary RLS. Male gender and ethnicity play significant roles in primary RLS, whereas female gender and iron deficiency may be the main risk factors associated with secondary RLS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|