The effect of perineural dexamethasone on duration of sciatic nerve blockade:a randomized, double-blind study
| Autor: | C. W. Henriksen, Jens Børglum, Rasmus W. Hauritz, Siska Bjørn, Thomas Fichtner Bendtsen, Kjartan Eskjaer Hannig |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Time Factors medicine.medical_treatment Dexamethasone 03 medical and health sciences 0302 clinical medicine Double-Blind Method 030202 anesthesiology Medicine Humans Prospective Studies Saline Aged Pain Postoperative business.industry Foot Dexamethasone/pharmacology Foot and ankle surgery Nerve Block Pain Postoperative/prevention & control General Medicine Middle Aged Sciatic Nerve Blockade Saphenous nerve Anesthesiology and Pain Medicine Opioid Anesthesia Foot/surgery Nerve block Ankle/surgery Female Sciatic nerve Ankle business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Hauritz, R W, Hannig, K E, Henriksen, C W, Børglum, J, Bjørn, S & Bendtsen, T F 2018, ' The effect of perineural dexamethasone on duration of sciatic nerve blockade : a randomized, double-blind study ', Acta Anaesthesiologica Scandinavica, vol. 62, no. 4, pp. 548-557 . https://doi.org/10.1111/aas.13054 |
| DOI: | 10.1111/aas.13054 |
| Popis: | Background: Major hindfoot and ankle surgery is associated with severe postoperative pain, which is effectively alleviated by combined sciatic and saphenous nerve blockade. Local anaesthetics with added dexamethasone consistently prolongs the duration of pain relief compared to local anaesthetics alone. However, whether the extended duration of pain relief is due to an effect on duration of sensorimotor block per se vs. systemic absorption of the dexamethasone is still not fully elucidated. We aimed to investigate the postoperative duration of sensorimotor blockade with either dexamethasone or saline added to bupivacaine-epinephrine. Methods: Fifty six patients scheduled for surgery were randomly assigned to a popliteal sciatic nerve block of 18 ml 0.5% bupivacaine-epinephrine with either 2 ml of 0.4% dexamethasone or 2 ml 0.9% normal saline added. Sensory and motor functions were tested every 30 min until normalized nerve functions. Primary outcome was time until complete return of sensorimotor functions. Results: Mean (SD) time until return of normal sensory and motor functions was 26 (6) vs. 16 (4) hours, P |
| Databáze: | OpenAIRE |
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