Hypercalcemia and diabetes insipidus in a patient previously treated with lithium
Autor: | Walid Khairallah, Ahmad Fawaz, Ghada El-Hajj Fuleihan, Edward M. Brown |
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Rok vydání: | 2007 |
Předmět: |
Parathyroidectomy
medicine.medical_specialty Lithium (medication) medicine.medical_treatment Urology Diabetes Insipidus Nephrogenic Risk Assessment Kidney Calculi Lithium Carbonate Internal medicine Humans Medicine Desmopressin Aged Hyperparathyroidism business.industry General Medicine Nephrogenic diabetes insipidus medicine.disease Long-Term Care Treatment Outcome Endocrinology Nephrology Diabetes insipidus Hypercalcemia Schizophrenia Female Kidney stones Hypernatremia business Follow-Up Studies medicine.drug |
Zdroj: | Nature Clinical Practice Nephrology. 3:397-404 |
ISSN: | 1745-8331 1745-8323 |
DOI: | 10.1038/ncpneph0525 |
Popis: | Background A 65-year-old woman presented with decreased oral intake, a reduced level of consciousness, hypercalcemia and hypernatremia. She had previously received lithium for 20 years for a schizoaffective disorder, but this treatment had been discontinued 3 years before presentation. Investigations Physical examination, laboratory studies including measurement of serum calcium and parathyroid hormone levels, measurement of urine and serum osmolalities before and after desmopressin administration, blood and urine cultures, and a CT scan of the abdomen. Diagnosis Urosepsis, dehydration, kidney stone disease, hyperparathyroidism, and nephrogenic diabetes insipidus. Management Hydration, antibiotics, intravenous pamidronate for rapid control of hypercalcemia, parathyroidectomy, surgical removal of the large kidney stones, a low-protein and low-sodium diet, and initiation of treatment with a thiazide diuretic. |
Databáze: | OpenAIRE |
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