Erythroferrone and iron status parameters levels in pediatric patients with iron deficiency anemia
| Autor: | Fady M. El Gendy, Hanaa E. Osheba, Mahmoud A El-Hawy, Amira M. F. Shehata |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Adolescent Iron Peptide Hormones Gastroenterology 03 medical and health sciences 0302 clinical medicine Hepcidin Internal medicine medicine Humans Child chemistry.chemical_classification biology medicine.diagnostic_test Anemia Iron-Deficiency Transferrin saturation business.industry Transferrin Infant Hematology General Medicine Erythroferrone medicine.disease Ferritin 030104 developmental biology Iron-deficiency anemia chemistry Case-Control Studies Child Preschool biology.protein Serum iron Female Hemoglobin business Biomarkers 030215 immunology |
| Zdroj: | European journal of haematology. 100(4) |
| ISSN: | 1600-0609 |
| Popis: | OBJECTIVES To investigate the link between serum erythroferrone (ERFE) levels and iron status parameters in pediatric patients with iron deficiency anemia. METHODS The study consisted of 66 children (36 with iron deficiency anemia and 30 healthy age- and gender-matched controls) who were investigated for serum levels of iron, total iron-binding capacity (TIBC) using automated chemistry analyzer, serum ferritin using electrochemiluminescence immunoassay and ERFE by specific enzyme-linked immunosorbent assay (ELISA) kit. RESULTS Serum erythroferrone levels in iron deficiency anemia patients (191.55 ± 83.74 pg/mL) were significantly higher than those in control group (42.22 ± 16.55 pg/mL) (P |
| Databáze: | OpenAIRE |
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