Recent advances in the management of diabetic retinopathy
| Autor: | Bilal Shaikh, Narin Osman, Nabeela K. Dulull, Faith A.A. Kwa, Thilini Thrimawithana, Uma Rai |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Pharmacology medicine.medical_specialty Microvascular complication Diabetic Retinopathy business.industry Disease progression Diabetic retinopathy Disease medicine.disease 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Diabetes mellitus Drug Discovery medicine Diabetes Mellitus Disease Progression Animals Humans Intensive care medicine business Pathological |
| Zdroj: | Drug discovery today. 24(8) |
| ISSN: | 1878-5832 |
| Popis: | Diabetic retinopathy (DR) is a microvascular complication of diabetes and is the leading cause of vision loss in people with diabetes. The current treatments do not target early stages of disease or impede disease progression. Therefore, the identification of new therapeutic targets, the development of novel therapies targeting early stages of the disease and accurate models that simulate pathological characteristics of this disorder are crucial. This review provides an overview of the pathological mechanisms underlying the development of DR, highlighting the recent advances in current and emerging treatments for DR. |
| Databáze: | OpenAIRE |
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