| Popis: |
These studies indicate that vitamin B complex restriction caused severe primary mental changes or aggravation of pre-existing psychotic trends among the psychotic subjects. The character of the mental changes appeared to depend on speed and severity of the deprivation. Patients whose B complex intake was so restricted that it contained 400 mcg. of thiamine and correspondingly small intake of other B complex factors showed diminution of psychomotor activity, dulling of affect, loss of interests and ambitions. In some of the severely depleted patients whose thiamine intake was restricted to 200 mcg. daily, serious emotional disturbances with loss of inhibitory control developed. In others, pre-existing affective trends such as hypomanic and mildly depressive features became markedly exaggerated. The formation of paranoid trends also was observed. Among the group moderately deprived of vitamin B complex the mental changes developed slowly in the course of 3 years. However, among the subjects severely deprive... |
