Low levels of morning salivary alpha-amylase activity predict higher number of depressive symptoms in a community sample of children
| Autor: | María Victoria Trianes, E. Maldonado, Eugenia Fernández, Carmen Ortiz, Alfredo Enguix, Mari Anneli Nislin |
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| Přispěvatelé: | [Francisco Maldonado, Enrique] Univ Malaga, Malaga, Spain, [Fernandez, Eugenia] Univ Malaga, Malaga, Spain, [Victoria Trianes, Maria] Univ Malaga, Malaga, Spain, [Ortiz, Carmen] Virgen de la Victoria Hosp, Malaga, Spain, [Enguix, Alfredo] Virgen de la Victoria Hosp, Malaga, Spain, [Nislin, Mari] Educ Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adrenal secretion
Saliva medicine.medical_specialty Observational Descriptive Study 16-year-olds Cortisol awakening response Stress Cortisol Fight-or-flight response 03 medical and health sciences Alpha-Amylase 0302 clinical medicine 030502 gerontology Internal medicine Disorder Psychology Medicine Major depression Children Immunoassay system General Psychology Depressive symptoms Morning First episode 030214 geriatrics business.industry Follow-up Depressive Symptoms Sex-differences BF1-990 Etiology Internalizing symptoms 0305 other medical science business Salivary α amylase |
| Zdroj: | Anales de Psicología, Vol 34, Iss 2, Pp 224-232 (2018) |
| Popis: | Models of the etiology of depressive disorders suggest that the onset of a depressive episode is the result of a complex phenomenon based on the interaction between genetic background, critical environmental factors such as life stressors and traumatic events, and the effects of neuroendocrine changes associated with the stress response. Numerous studies have highlighted the usefulness of morning cortisol (C) as a potential predictor of depressive episodes. The aim of this study was to compare the effectiveness of C, salivary alpha-amylase (sAA) activity/output, and the sAA/C ratio in predicting depressive symptoms in a community sample of 99 children aged 8-11 years old. Two saliva samples were obtained in the morning on two different school days. Teachers described their pupils' behavior by using the internalizing problems scales of the Teacher’s Report Form (TRF) questionnaire. Our results indicate that, regardless of gender, the best predictor of depressive/withdrawal scores and overall internalizing scores on the TRF was lower mean morning levels of sAA activity. Hence, sAA could be proposed as a biological marker for the risk of developing a first episode of depressive illness in child samples. |
| Databáze: | OpenAIRE |
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