Trans-palmitoleic acid (trans-9-C16:1, or trans-C16:1 n-7): Nutritional impacts, metabolism, origin, compositional data, analytical methods and chemical synthesis. A review

Autor: Etienne Guillocheau, Philippe Legrand, Vincent Rioux
Přispěvatelé: Laboratoire de Biochimie et Nutrition Humaine, AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Meat
Biology
Health benefits
Bioinformatics
Biochemistry
Rumenic acid
Multidisciplinary review
Fatty Acids
Monounsaturated
03 medical and health sciences
chemistry.chemical_compound
Trans-vaccenic acid
[SDV.IDA]Life Sciences [q-bio]/Food engineering
Dietary Fatty Acid
Palmitoleic acid
Animals
Humans
Linoleic Acids
Conjugated
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
Obesity
2. Zero hunger
chemistry.chemical_classification
Clinical Trials as Topic
030102 biochemistry & molecular biology
integumentary system
Fatty acid
Trans-Palmitoleic acid
Stereoisomerism
Type 2 diabetes
General Medicine
Metabolism
Ruminants
Trans Fatty Acids
Ruminant milk
3. Good health
Diet
030104 developmental biology
Milk
chemistry
Diabetes Mellitus
Type 2
Human plasma
Cardiovascular Diseases
Dietary Supplements
Hydrogenation
Ruminant meat
Zdroj: Biochimie
Biochimie, Elsevier, 2020, 169, pp.144-160. ⟨10.1016/j.biochi.2019.12.004⟩
ISSN: 0300-9084
DOI: 10.1016/j.biochi.2019.12.004⟩
Popis: International audience; Since the early 2010s, dietary trans-palmitoleic acid (trans-9-hexadecenoic acid, trans-9-C16:1 in the Δ-nomenclature, trans-C16:1 n-7 in the Ω-nomenclature, TPA) has been epidemiologically associated with a lower risk of type 2 diabetes in humans. Thanks to these findings, TPA has become a nutrient of interest.However, there is a lot of unresolved crucial questions about this dietary fatty acid. Is TPA a natural trans fatty acid? What kind of foods ensures intakes in TPA? What about its metabolism? How does dietary TPA act to prevent type 2 diabetes? What are the biological mechanisms involved in this physiological effect? Clearly, it is high time to answer all these questions with the very first review specifically dedicated to this intriguing fatty acid. Aiming at getting an overview, we shall try to give an answer to all these questions, relying on appropriate and accurate scientific results.Briefly, this review underlines that TPA is indeed a natural trans fatty acid which is metabolically linked to other well-known natural trans fatty acids. Knowledge on physiological impacts of dietary TPA is limited so far to epidemiological data, awaiting for supplementation studies. In this multidisciplinary review, we also emphasize on methodological topics related to TPA, particularly when it comes to the quantification of TPA in foods and human plasma. As a conclusion, we highlight promising health benefits of dietary TPA; however, there is a strong lack in well-designed studies in both the nutritional and the analytical area.
Databáze: OpenAIRE
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