Platelet sensitivity to a prostacyclin analogue in normal and pathological pregnancy
Autor: | D.G. Kieback, T.H. Lippert, R.C. Briel |
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Rok vydání: | 1984 |
Předmět: |
Blood Platelets
medicine.medical_specialty Platelet Aggregation Physiology Pregnancy in Diabetics Prostacyclin Gestational Age Biochemistry Preeclampsia Endocrinology Pre-Eclampsia Pregnancy Internal medicine Medicine Humans Platelet Iloprost business.industry Postpartum Period Gestational age medicine.disease Epoprostenol eye diseases Depression Chemical Gestation Female business Postpartum period medicine.drug |
Zdroj: | Prostaglandins, leukotrienes, and medicine. 13(3) |
ISSN: | 0262-1746 |
Popis: | Platelet sensitivity to a prostacyclin analogue (PSP) was investigated at different stages of normal and pathological pregnancies. During uncomplicated pregnancy PSP decreased progressively by about 30% and returned to almost normal values in the puerperium. In pre-eclamptic women PSP was reduced by 49% and in pregnant diabetics by 50% compared with normal pregnant individuals of corresponding gestational age. Reduced PSP in normal and pathological pregnancy seems to be another aspect of increased coagulability and platelet aggregation found in these patients. |
Databáze: | OpenAIRE |
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