Benign neuromyelitis optica is rare in Japanese patients
Autor: | Tomohiko Uchida, Akiyuki Uzawa, Masahiro Mori, Saeko Masuda, Hiroki Masuda, Satoshi Kuwabara, Mayumi Muto |
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Rok vydání: | 2014 |
Předmět: |
Adult
Pediatrics medicine.medical_specialty Disease duration Disease Cohort Studies Disability Evaluation Asian People medicine Humans Good outcome Aged Retrospective Studies Expanded Disability Status Scale Neuromyelitis optica business.industry Multiple sclerosis Neuromyelitis Optica Middle Aged Prognosis medicine.disease Neurology Disease Progression Physical therapy Female Neurology (clinical) Early phase business |
Zdroj: | Multiple Sclerosis Journal. 21:1204-1208 |
ISSN: | 1477-0970 1352-4585 |
Popis: | Good-outcome neuromyelitis optica (NMO) is defined as an Expanded Disability Status Scale (EDSS) score of ≤3.0 at 10 years after onset. The clinical courses of 80 consecutive patients with NMO were analyzed to identify the frequency and features of Japanese patients with good-outcome NMO. Of the 80 patients, 37 had a disease duration of >10 years; of these, eight (21.6%) presented a good outcome. These cases presented lower EDSS scores during the early phase of disease compared with those with conventional NMO. However, half of these patients developed severe disabilities later on, indicating that truly benign NMO is rare. |
Databáze: | OpenAIRE |
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