Impact of radon and combinatory radon/carbon dioxide spa on pain and hypertension: Results from the explorative RAD-ON01 study
Autor: | Paul F. Rühle, Benjamin Frey, Rainer Fietkau, Hong Tiep Phan, Claudia Fournier, Gerhart Klein, Udo S. Gaipl, Tatiana Rung |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty chemistry.chemical_element Radon Gastroenterology Health Resorts 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Rheumatology Internal medicine medicine Humans Pain Management 030212 general & internal medicine Beneficial effects Aged 030203 arthritis & rheumatology business.industry Balneology Low dose Middle Aged respiratory tract diseases Carbonated Water chemistry Pain reduction Carbon dioxide Hypertension Female business |
DOI: | 10.6084/m9.figshare.5944039.v1 |
Popis: | Objectives: Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain-reducing effects of very low doses of radon by adding carbon dioxide water and its impact on heart rate variability (HRV), blood pressure and free radicals. Methods: 97 of 103 patients receiving radon spa (1.200 Bq/l at 34 °C or 600 Bq/l, 1 g/l CO2 at 34 °C) were monitored before and at three different time points after therapy. Individual pain perception was analyzed and the capability to process radicals. At each time point, the hypertensive patients (n = 46) were examined over 24 h for blood pressure and HRV. Results: Long-term pain reduction was observed in the majority of patients. A modulation of superoxide dismutase was identified, presumably representing a priming effect for lowering radiation stress. Further, lowering of blood pressure, especially in those patients who additionally received carbon dioxide, was seen. Radon did in particular impact on HRV implying lasting relaxation effects. Conclusion: Radon/carbon dioxide spa efficiently reduces pain. In particular, patients simultaneously suffering from painful and cardiovascular diseases should be treated by combination of radon and CO2. |
Databáze: | OpenAIRE |
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