Postnatal intravenous steroids and long-term neurological outcome: recommendations from meta-analyses
| Autor: | S J Newell, H L Yates |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Lung Diseases
medicine.medical_specialty Pediatrics Developmental Disabilities MEDLINE Infant Premature Diseases Drug Administration Schedule medicine Humans Intensive care medicine Glucocorticoids Confusion Evidence-Based Medicine business.industry Cerebral Palsy Infant Newborn Obstetrics and Gynecology General Medicine Prognosis Chronic disease Steroid use Meta-analysis Pediatrics Perinatology and Child Health Chronic Disease Injections Intravenous medicine.symptom Intravenous steroids business Infant Premature |
| Zdroj: | Archives of disease in childhood. Fetal and neonatal edition. 97(4) |
| ISSN: | 1468-2052 |
| Popis: | Postnatal steroids have been widely used to facilitate the extubation of ventilator-dependent preterm infants. Reports published in the late 1990s and early 2000s raised concerns about their long-term impact on neurodevelopmental outcomes. Since then, postnatal steroid use has declined sharply, but they continue to be regarded by many clinicians as an essential part of neonatal care, and there is considerable confusion as to the most appropriate time to use them. This review examines the meta-analyses of the relationship between intravenous postnatal steroids and neurodevelopmental impairment, and provides recommendations for their use based upon that body of evidence. |
| Databáze: | OpenAIRE |
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