Maternal parity and functional contractility of human myometrium in vitro in the third trimester of pregnancy
| Autor: | Gillian A. Ryan, John J. Morrison, Sarah M. Nicholson, Denis J. Crankshaw |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Human myometrium Pregnancy Trimester Third Third trimester Tissue Culture Techniques Contractility Uterine Contraction Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Humans Medicine 030212 general & internal medicine Cesarean delivery Young adult Cesarean Section business.industry Obstetrics Obstetrics and Gynecology medicine.disease In vitro Parity Pediatrics Perinatology and Child Health Myometrium Female business Parity (mathematics) |
| Zdroj: | Journal of Perinatology. 39:439-444 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/s41372-019-0312-2 |
| Popis: | It is well established that the duration of the first and second stages of labor are shorter in parous women than in their nulliparous counterparts, a phenomenon not well understood. The aim was to examine the effect of maternal parity on contractile parameters of human myometrium. Myometrial strips were excised from n = 74 women at cesarean delivery and recordings of contractile activity analyzed and compared across three clinical groups: 1. No previous delivery (P0); 2. One previous delivery (P1); 3. Greater than one previous delivery (P>1). There was a trend towards greater mean contractile force in the P>1 group than the P1 and P0 groups (P = 0.412). Frequency of contractions was less in the P1 group than in the P0 and P>1 groups(P = 0.027). No differences were observed in relation to all other parameters. Excluding frequency, no intrinsic differences were observed in the functional parameters of human uterine contractions in relation to parity. |
| Databáze: | OpenAIRE |
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