Deep remission from induction chemotherapy predicts favorable long-term survivals in early stage extranodal nasal NK/T-cell lymphoma receiving sequential chemotherapy and radiation

Autor: Fei Qi, Wenyuan Zhou, Yan Xie, Yan Sun, Meng Wu, Yue Chai, Bo Chen, Ningjing Lin, Weiping Liu, Ning Ding, Yexiong Li, Mei Dong, Yuqin Song, Jun Zhu
Rok vydání: 2022
Předmět:
Zdroj: Aging. 14(21)
ISSN: 1945-4589
Popis: We aimed to assess the association between induction chemotherapy (CT) response and survivals and to explore an induction CT response-adapted treatment strategy for localized extranodal NK/T-cell lymphoma (NKTCL) receiving first-line sequential CT and radiation (RT).We retrospectively reviewed the data of patients with localized NKTCL receiving first-line CT+RT from 2010 to 2020 at two independent institutes (primary cohort,Patients with initial complete remission (CR) had higher final CR rate than the others (99.1% vs. 78.7%,Deep remission from induction CT was associated with favorable survivals in localized NKTCL receiving CT+RT, and an induction CT response-adapted individualized treatment strategy might be recommended in clinical practice.
Databáze: OpenAIRE