A case of pernicious anemia requiring differential diagnosis of autoimmune hemolytic anemia complication
| Autor: | Toshimasa Takahashi, Saki Todo, Takeshi Sugimoto, Kenta Hara, Yoshiro Yasutomo, Kohei Okamoto, Takashi Arai, Katsuhito Nishiyama, Yasushi Nakagawa, Koichi Yokono |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Atrophic gastritis business.industry Anemia Case Report medicine.disease Microbiology Gastroenterology Hemolysis 03 medical and health sciences 0302 clinical medicine Infectious Diseases 030220 oncology & carcinogenesis Internal medicine mental disorders medicine Parasitology 030212 general & internal medicine Vitamin B12 Autoimmune hemolytic anemia Differential diagnosis Complication business pernicious anemia |
| Zdroj: | Oxford Medical Case Reports |
| ISSN: | 2053-8855 |
| Popis: | An 80-year-old female was admitted to our hospital due to malaise. The initial diagnosis on admission was pernicious anemia (PA), Hashimoto thyroiditis and autoimmune atrophic gastritis. Autoimmune hemolytic anemia was suspected because direct antiglobulin test (DAT) was positive. Treatment with vitamin B12 improved anemia, with the disappearance of hemolysis. In some cases, PA patients with positive DAT may have hemolysis without the involvement of the autoimmune mechanism. Therefore, it is important to carefully assess PA patients with hemolysis and positive DAT for the prevention of unnecessary administration of steroid therapy. |
| Databáze: | OpenAIRE |
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