Nasal Provocation Tests in the Diagnosis of Urticaria Induced by Acetylsalicylic Acid

Autor: Maria F. Ferreira, Antero G. Palma-Carlos, Elza M. Tomaz, Maria A. Spínola, Maria L. Oliveira, Maria H. Clode
Rok vydání: 1997
Předmět:
Zdroj: Allergy and Asthma Proceedings. 18:319-322
ISSN: 1088-5412
DOI: 10.2500/108854197778590515
Popis: Nasal provocation tests with lysine acetylsalicylic acid (ASA) have been used in the diagnosis of ASA-induced asthma and rhinitis. To establish its possible role in identifying aspirin sensitivity manifested by urticaria or angioedema, 18 patients suffering from chronic or acute recurring urticaria/angioedema (10 ASA-sensitive and 8 ASA-nonsensitive) were submitted to nasal provocation tests with freshly prepared solutions of lysine ASA. Clinical response and variation of nasal expiratory peak-flow were evaluated, classified according to previously defined scores, and compared. The results showed a significant difference between ASA-sensitive and ASA-nonsensitive patients, suggesting that this test can be an important diagnostic tool for ASA-induced urticaria/angioedema.
Databáze: OpenAIRE