Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos
| Autor: | Y. E. Sopena De Kracoff, A M Ferramola de Sancovich, H.A. Sancovich, N.L. Pauza |
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| Rok vydání: | 2002 |
| Předmět: |
Ontogeny
Porphobilinogen deaminase Embryogenesis Yolk sac membrane Age Factors Porphobilinogen Synthase General Medicine Chick Embryo Biology Chick embryos Hydroxymethylbilane Synthase Cytosol Biochemistry Liver Spectrophotometry Dehydratase embryonic structures Animals Animal Science and Zoology Erythropoietic tissue Food Science Yolk Sac |
| Zdroj: | British poultry science. 43(2) |
| ISSN: | 0007-1668 |
| Popis: | 1. Chick embryos of 7, 9, 11, 12, 13, 14, 15, 17 and 19 d of embryonic development were examined to determine the activities of 5-aminolevulinic dehydratase (ALA-D, EC 4.2.1.24) and porphobilinogen deaminase (PBG-D, EC 4.3.1.8). 2. Liver and yolk sac membrane ALA-D specific activities showed a maximum between 12 and 13 d of embryonic development, yolk sac membrane PBG-ase activity a maximum at 9 d and at 7 d in liver. Total activities of ALA-D and PBG-D were not constant during the course of embryonic development but probably related to the changes of intensity of haem synthesis. 3. ALA-D and PBG-ase activities were higher in yolk sac membrane than in liver, showing the importance of the yolk sac membrane as erythropoietic tissue. PBG-D catalysed the rate-limiting reaction of the cytosolic steps in the biosynthetic pathway in both tissues. |
| Databáze: | OpenAIRE |
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