| Autor: |
Yamasaki, Maria, Makino, Takashi, Seik-Soon Khor, Toyoda, Hiromi, Miyagawa, Taku, Xiaoxi Liu, Kuwabara, Hitoshi, Kano, Yukiko, Shimada, Takafumi, Sugiyama, Toshiro, Nishida, Hisami, Sugaya, Nagisa, Tochigi, Mamoru, Otowa, Takeshi, Okazaki, Yuji, Kaiya, Hisanobu, Kawamura, Yoshiya, Miyashita, Akinori, Kuwano, Ryozo, Kasai, Kiyoto, Tanii, Hisashi, Sasaki, Tsukasa, Honda, Makoto, Tokunaga, Katsushi |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.6084/m9.figshare.12045759 |
| Popis: |
Additional file 1: Figure S1. Overview of the study. CNVs identified from each detection method were filtered and analyzed independently. Figure S2. CNV frequency and proportion of dosage-sensitive genes overlapped by CNVs. The x axis shows the frequency of CNVs in each patient and healthy individual. The y axis shows the proportion of ohnologs with SSD, singletons, ohnologs without SSD, or non-ohnologous duplicates. Figure S3. Enrichment of ohnologs in CNVs observed in five neuropsychiatric diseases according to the definitions by Singh, PP et al. Figure S4. Enrichment of dosage-sensitive genes in CNVs observed in five neuropsychiatric diseases with the use of another software, CNV Workshop. Figure S5. Enrichment of ohnologs in CNVs observed in five neuropsychiatric diseases with the use of another software, CNV Workshop. Figure S6. Enrichment of genes with expression sensitivity only in brain in CNVs observed in five neuropsychiatric diseases with the use of another software, CNV Workshop. Table S1. Enrichment of dosage-sensitive ohnologs in individuals with narcolepsy using CNVs detected by PennCNV. Table S2. Enrichment of dosage-sensitive ohnologs in individuals with autism using CNVs detected by PennCNV. Table S3. Enrichment of dosage-sensitive ohnologs in individuals with panic disorders using CNVs detected by PennCNV. Table S4. Enrichment of dosage-sensitive ohnologs in individuals with essential hypersomnia using CNVs detected by PennCNV. Table S5. Enrichment of dosage-sensitive ohnologs in individuals with Alzheimer disease using CNVs detected by PennCNV. Table S6. Combined enrichment of dosage-sensitive genes and genes with expression sensitivity only in brain in CNVs observed in five neuropsychiatric diseases with the use of another software, CNV Workshop. Table S7. Disease-specific regions for five neuropsychiatric diseases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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