Chitooligosaccharides Stimulate Atlantic Salmon, Salmo salar L., Head Kidney Leukocytes to Enhanced Superoxide Anion Production In Vitro

Autor: Audny Johansen, Even Stenberg, Jarl Bøgwald, Asbjørn Gildberg, Kari Steiro, James Hoffman
Rok vydání: 1997
Předmět:
Zdroj: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 118:105-115
ISSN: 1096-4959
DOI: 10.1016/s0305-0491(97)00021-7
Popis: Chitosans and chitooligosaccharides stimulated Atlantic salmon, Salmo salar L., head kidney leukocytes in vitro to produce elevated levels of superoxide anion. Both soluble and insoluble chitooligosaccharides were stimulatory 2 and 7 days after addition. Protein-chitooligosaccharide conjugates were also stimulatory in vitro both at 2 and 7 days after addition. Deacetylation seemed to be of little importance for the stimulatory capacity. High concentrations of the 80% deacetylated chitosan/chitooligosaccharides were toxic to the leukocytes as judged by reduced reduction of nitroblue tetrazolium and morphology.
Databáze: OpenAIRE