Quantification of rosiglitazone in rat plasma and tissues via LC-MS/MS: Method development, validation, and application in pharmacokinetic and tissue distribution studies

Autor:	Kusuma Kumari Garikapati, Ravi Kiran Ammu V. V. V., Praveen Thaggikuppe Krishnamurthy, Narenderan S. T., Babu B., Krishnaveni Nagappan
Rok vydání:	2021
Předmět:	Pharmacology Pioglitazone Clinical Biochemistry Reproducibility of Results General Medicine Biochemistry Analytical Chemistry Rats Rosiglitazone Tandem Mass Spectrometry Drug Discovery Animals Tissue Distribution Molecular Biology Chromatography Liquid
Zdroj:	Biomedical chromatography : BMCREFERENCES. 36(5)
ISSN:	1099-0801
Popis:	A bioanalytical method for the quantification of rosiglitazone in rat plasma and tissues (adipose tissue, heart, brain, bone, and kidney) using LC-MS/MS was developed and validated. Chromatographic separation was achieved on a Gemini C
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abb443598b3580a1cb8f3290089e6b3 https://pubmed.ncbi.nlm.nih.gov/34993979 Zobrazit plný text záznamu Plný text