Is Chloral Hydrate/Hydroxyzine a Good Option for Paediatric Dental Outpatient Sedation?
| Autor: | Rodolfo Fragoso-Ríos, Rocío E. Zayas-Carranza, Diana Moyao-García, Verónica Avalos-Arenas, Alejandro A Nava-Ocampo |
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| Rok vydání: | 1998 |
| Předmět: |
Time Factors
medicine.drug_class Anesthesia Dental Sedation Chloral hydrate Conscious Sedation Child Behavior Statistics Nonparametric Double-Blind Method Clinical investigation medicine Humans Hypnotics and Sedatives Chloral Hydrate High rate Hydroxyzine Analysis of Variance business.industry Crying Dental procedures Hemodynamics Infant General Medicine Anesthetics Combined Child Preschool Sedative Anesthesia medicine.symptom business medicine.drug |
| Zdroj: | Current Medical Research and Opinion. 14:219-226 |
| ISSN: | 1473-4877 0300-7995 |
| DOI: | 10.1185/03007999809113362 |
| Popis: | The primary objective of this study was to evaluate in a random double-blind design, the sedative and behavioural responses of children undergoing outpatient paediatric dental procedures receiving either chloral hydrate (CH) alone or in combination with hydroxyzine. Forty American Society of Anaesthesiologists class I children (21 to 36 months of age) were randomly allocated to receive either 70 mg/kg CH alone or with 2 mg/kg hydroxyzine. The degree of crying, movement and overall behaviour was evaluated during treatment at different times. The combination of chloral hydrate/hydroxyzine (CH/H) significantly decreased crying and movement in relation to the effect induced by CH alone (p0.05) only at 45-60 min following the insertion of a rubber dam, whereas the overall behavior in both groups was no different throughout the dental procedures. In conclusion, our study demonstrated that hydroxyzine increased the effect of CH. However, because of the presence of high rates of oxygen desaturations and of deep sedation, careful use of this drug combination should be stressed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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